News Flash:
March 31, 2017: DeMix R package is available. DeMix includes DeMix-Bayes for two-component mixture and DeMixT for three-component mixture. It can be downloaded from Github:Download here.Installation under R:'devtools::install_github("wwylab/DeMix")'
January 27, 2017: Our LFSPRO paper is online at CEBP. link to the paper. Congrats to Gang!
January 20, 2017: Our Bayesian semiparametric modeling work for Li-Fraumeni syndrome cancer outcomes is available on arXiv. Download preprint here
August 26, 2016: Download the source code of our mutation caller MuSE here.
August 26, 2016: MuSE is now online at Genome Biology.
Download text here
June 29, 2016: Congrats to Wenyi, the Program Chair-Elect for ASA Section on Statistics in Genetics and Genomics.
April 21, 2016: Wenyi Wang will give a talk at the Annual LiFE Consortium & LFSA Conference. Jialu Li and Elissa Dodd will also give posters there on their LFS projects. Exciting!!
Link to the LFS conference here.
April 15, 2016: Congratulations to Zeya Wang for being selected as the only statistics graduate student to participate in the IBM Rice Global internship program!
March 7, 2016: Zeya Wang and Jialu Li are both giving talks at the ENAR 2016 conference at Austin. Enjoy!
Jan 6, 2016: Amir's paper on BVS-NLP for binary outcomes is published on Bioinformatics. [Abstract][PDF] Congrats!!
Oct 19, 2015: First member of the lab, a newly-minted PhD, Gang Peng will be joining Professor Hongyu Zhao's group at Yale University Department of Biostatistics as a postdoctoral fellow. Farewell and best of luck!!
Oct 5, 2015: Zeya Wang is giving a poster presentation on the deconvolution of three mixing components in tumor samples, DeMix-T, at ASHG 2015 this Friday. Good luck!
Sep 18, 2015: LFSPRO_1.0.4 is now available for download. LFSPRO is also officialy released as part of the R package BayesMendelv2.1-2.
Sep 15, 2015: Warm welcomes to new members of the group: postdoctoral fellows Xuedong (Peter) Pan and Nilotpal (Nil) Sanyal!
Sep 1, 2015: Congrats to Wenyi for promotion to Tenured Associate Professor!
Aug 31, 2015: Big congrats to Gang Peng for having successfully defended his thesis! Well done!!
June 9, 2015: MuSE1.0rc can be downloaded from here.
Apr 27, 2015: MuSE1.0b is available here.
Feb 20, 2015: Congrats to Yu Fan on his successful renewal of the CCBTP fellowship.
Feb 10, 2015: Congrats to Gang Peng for receiving a GSBS student travel award to present his work on LFSpro at the ENAR spring meeting, Miami!
Feb 6, 2015: Farewell to Seung Jun! Good luck with your new journey at Korea University! Pictures from the farewell party
Dec 3, 2014: Final results of the ICGC-TCGA Dream Mutation Calling Challenge are here.
Nov 18, 2014: Our group member, GSBS student, Jialu Li has passed his PhD qualifying exam. Congratulations!!
Oct 30, 2014:
Software release:
1. Our somatic mutation caller MuSE can be downloaded from here.
2. R package LFSpro for TP53 mutation carrier probability estimation in families with Li-Fraumeni Syndrome is available now.
New publication: FamSeq is online at PLOS Computational Biology.
Oct 29, 2014: Seung Jun Shin takes on a Tenure-Track Assistant Professor position at Korea University, Seoul, South Korea. Congratulations, Seung Jun!!
Oct 1 2014: Dr. Wenyi Wang has received a 5-year R01 grant on Statistical methods for analysis of heterogeneous tumor samples from the National Cancer Institute. Congrats!!
Sep 1 2014: We have a new postdoc fellow join our group: Tsung-heng Tsai, from Virginia Tech. Welcome Tsung-heng!
Updated Sep 2 2014: Our FamSeq software paper is in press on PLOS Computational Biology.
Apr 25 2014: Software release: FamSeq can now run on GPUs (graphic processing units). If you have a computer equipped with a CUDA-enabled graphic card, you can gain computational efficiency for variant calling of DNA sequencing data from families by running FamSeq-GPU!
Apr 18 2014: Yu Fan is awarded the Keck postdoctoral fellowship by the Computational Cancer Biology Training Program from the Golf Coast Consortia for Quantitative Biomedical Sciences. See details about CCBTP.
March 30 2014: Our new somatic mutation caller MuSE ranked #2 at the DREAM Mutation Calling challenge Round 2. Keep up the good work, team!!
Follow the challenge
See details about MuSE
January 2014: Zeya Wang has passed the doctoral qualifying exam at Rice Statistics. Congratulations!!
Our new group member, GSBS 2nd year graduate student Jialu Li, published his master thesis work on Nature this month. Congratulations!! Link to the article
Dr. Wenyi Wang has received a 2-year Individual Investigator Research Award (IIRA) on personalized risk assessment for families with Li-Fraumeni Syndrome by the Cancer Prevention Research Institute of Texas (CPRIT). Congratulations!
Our paper on developing multiplex target capture technology for high-throughput sequencing of patient samples is published on Genome Medicine. Link to the paper
Our paper on studying tumor heterogeneity is published on Bioinformatics. Link to the paper, Link to the software
GenomeWeb This Week in PNAS: Rare variant detection using family-based sequencing analysis. PNAS Feb 2013. [Abstract]