2018 News


Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration will be published by iScience! Full Text

  • October 27, 2018

Our Bayesian estimation of a semiparametric recurrent event model for estimation of multiple primary cancers paper has been accepted by Biostatistics! Full Text

  • September 9, 2018

Our lab has developed is a new consensus clustering for subclonal reconstruction software, CSR (pronounced "Caesar") It can be downloaded from Github.

  • May 5, 2018

A huge endeavor of the Pan-Cancer Analysis Working Group (PCAWG): Portraits of genetic intra-tumour heterogeneity (ITH) and subclonal selection across cancer types.

  • May 5, 2018

Our first statistical modeling work for the Li-Fraumeni Syndrome (LFS) is acceptd by Journal of the American Statistical Association after a 3-year journey! Congrats everyone!

  • April 29, 2018

We developed a new software R package called Famdenovo: predicting the probability of de novo status of a germline mutation in familial diseases.

  • Janurary 20, 2017

2017 News


Our TAMU collaborators Amir and Val's latest work on Bayesian variable selection for survival outcomes is on arXiv.

  • December 10, 2017

Congratulations to the new graduates, Zeya Wang and Jialu Li!

  • April 12, 2017

DeMix R package is available. DeMix includes DeMix-Bayes for two-component mixture and DeMixT for three-component mixture. It can be downloaded from Github:Download here.

  • March 31, 2017

Our LFSPRO paper is online at CEBP. link to the paper. Congrats to Gang!

  • January 27, 2017

Our Bayesian semiparametric modeling work for Li-Fraumeni syndrome cancer outcomes is available on arXiv. Download preprint here

  • Janurary 20, 2017

2016 News

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  • Download the source code of our mutation caller MuSE here.

  • MuSE is now online at Genome Biology. Download text here.
    • Augsut 26, 2016


  • Congrats to Wenyi, the Program Chair-Elect for ASA Section on Statistics in Genetics and Genomics. .
    • June 29, 2016


  • Wenyi Wang will give a talk at the Annual LiFE Consortium & LFSA Conference. Jialu Li and Elissa Dodd will also give posters there on their LFS projects. Exciting!! Link to the LFS conference here.
    • April 21, 2016


  • Congratulations to Zeya Wang for being selected as the only statistics graduate student to participate in the IBM Rice Global internship program! .
    • April 15, 2016


  • Zeya Wang and Jialu Li are both giving talks at the ENAR 2016 conference at Austin. Enjoy!.
    • March 7, 2016


  • Amir's paper on BVS-NLP for binary outcomes is published on Bioinformatics. [Abstract][PDF] Congrats!! .
    • January 6, 2016


    2015 News

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  • First member of the lab, a newly-minted PhD, Gang Peng will be joining Professor Hongyu Zhao's group at Yale University Department of Biostatistics as a postdoctoral fellow. Farewell and best of luck!!.
    • October 19, 2015


  • Zeya Wang is giving a poster presentation on the deconvolution of three mixing components in tumor samples, DeMix-T, at ASHG 2015 this Friday. Good luck!
    • October 5, 2015


  • LFSPRO_1.0.4 is now available for download. LFSPRO is also officialy released as part of the R package BayesMendelv2.1-2
    • September 18, 2015


  • Warm welcomes to new members of the group: postdoctoral fellows Xuedong (Peter) Pan and Nilotpal (Nil) Sanyal!
    • September 15, 2015


  • Congrats to Wenyi for promotion to Tenured Associate Professor!
    • September 1, 2015


  • Big congrats to Gang Peng for having successfully defended his thesis! Well done!!
    • August 31, 2015


  • MuSE1.0rc can be downloaded from here
    • June 9, 2015


  • MuSE1.0b is available here
    • April 27, 2015


  • Congrats to Yu Fan on his successful renewal of the CCBTP fellowship.
    • Februrary 20, 2015


  • Congrats to Gang Peng for receiving a GSBS student travel award to present his work on LFSpro at the ENAR spring meeting, Miami!
    • February 10, 2015


  • Farewell to Seung Jun! Good luck with your new journey at Korea University!
    • February 6, 2015


    2014 News

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  • Final results of the ICGC-TCGA Dream Mutation Calling Challenge are here..
    • December 3, 2014


  • Our group member, GSBS student, Jialu Li has passed his PhD qualifying exam. Congratulations!!
    • November 18, 2014


  • Software release:
      1. Our somatic mutation caller MuSE can be downloaded from here.
      2. R package LFSpro for TP53 mutation carrier probability estimation in families with Li-Fraumeni Syndrome is available now.
      New publication: FamSeq is online at PLOS Computational Biology.
    • October 30, 2014


  • Seung Jun Shin takes on a Tenure-Track Assistant Professor position at Korea University, Seoul, South Korea. Congratulations, Seung Jun!!
    • October 29, 2014


  • Dr. Wenyi Wang has received a 5-year R01 grant on Statistical methods for analysis of heterogeneous tumor samples from the National Cancer Institute. Congrats!!
    • October 1, 2014


  • Our FamSeq software paper is in press on PLOS Computational Biology.
    • September 2, 2014


  • We have a new postdoc fellow join our group: Tsung-heng Tsai, from Virginia Tech. Welcome Tsung-heng!
    • September 1, 2014


  • Software release: FamSeq can now run on GPUs (graphic processing units). If you have a computer equipped with a CUDA-enabled graphic card, you can gain computational efficiency for variant calling of DNA sequencing data from families by running FamSeq-GPU!
    • April 25, 2014


  • Yu Fan is awarded the Keck postdoctoral fellowship by the Computational Cancer Biology Training Program from the Golf Coast Consortia for Quantitative Biomedical Sciences. See details about CCBTP.
    • April 18, 2014


  • Our new somatic mutation caller MuSE ranked #2 at the DREAM Mutation Calling challenge Round 2. Keep up the good work, team!! Follow the challenge See details about MuSE
    • March 30, 2014


  • Congrats to Yu Fan on his successful renewal of the CCBTP fellowship.
    • Februrary 20, 2015


  • Zeya Wang has passed the doctoral qualifying exam at Rice Statistics. Congratulations!!
    • January, 2014


  • Our new group member, GSBS 2nd year graduate student Jialu Li, published his master thesis work on Nature this month. Congratulations!! Link to the article
    • January, 2014


  • Dr. Wenyi Wang has received a 2-year Individual Investigator Research Award (IIRA) on personalized risk assessment for families with Li-Fraumeni Syndrome by the Cancer Prevention Research Institute of Texas (CPRIT). Congratulations!
    • January, 2014


  • Our paper on developing multiplex target capture technology for high-throughput sequencing of patient samples is published on Genome Medicine. Link to the paper
    • January, 2014


  • Our paper on studying tumor heterogeneity is published on Bioinformatics. Link to the paper, Link to the software
    • January, 2014